Erdafixen (Erdafitinib 4mg)

Erdafixen is a kinase inhibitor used to treat adult patients with locally advanced or metastatic urothelial carcinoma (mUC) who have susceptible FGFR3 genetic alterations. It is indicated for patients whose disease has progressed following at least one prior systemic therapy. Patient selection should be guided by an FDA-approved companion diagnostic for Erdafitinib.

Erdafitinib Dosage:

Confirm the presence of FGFR3 genetic alterations in tumor specimens prior to initiation of treatment with ERDAFITINIB.

• Recommended initial dosage: 8 mg orally once daily with a dose increase to 9 mg daily if criteria are met.

• Swallow whole with or without food.

Erdafitinib price in India

Erdafitinib cost in India online pharamcy is only 5% of Erdafitinib price in United States

Erdafitinib may cause serious side effects, including:

• Eye Problems: Eye issues are common with ERDAFITINIB and may become severe. These include dry or inflamed eyes, corneal inflammation, and retinal disorders. Inform your healthcare provider immediately if you experience blurred vision, vision loss, or other visual changes. To help prevent dry eyes, use artificial tears, hydrating eye gels, or lubricating ointments at least every two hours while awake. Your healthcare provider will arrange regular eye specialist visits during treatment.

• High Phosphate Levels (Hyperphosphatemia): Elevated phosphate levels in the blood are common but can be serious, potentially leading to mineral buildup in body tissues. Your healthcare provider will monitor your phosphate levels between days 14 and 21 after starting treatment, then monthly.

  • You may need dietary adjustments, phosphate-lowering therapy, or modifications to your ERDAFITINIB dosage.

  • Contact your healthcare provider immediately if you experience painful skin lesions, muscle cramps, or numbness/tingling around your mouth.

Common Side Effects of ERDAFITINIB

• Nail separation or poor nail formation

• Mouth sores

• Diarrhea

• Increased blood creatinine levels

• Elevated alkaline phosphatase levels

• Liver function changes

• Anemia (low red blood cell count)

• Low sodium levels

• Fatigue

• Dry mouth

• Dry skin

• Low phosphate levels

• Decreased appetite

• Altered sense of taste

• Constipation

• Increased calcium levels

• Dry eye

• Hand-foot syndrome (redness, swelling, peeling, tenderness on hands/feet)

• High potassium levels

• Hair loss

• Fluid buildup behind the retina

When to Contact Your Healthcare Provider

Inform your healthcare provider immediately if you experience:

• Nail issues such as nail separation, pain, bleeding, breakage, color/texture changes, or infections around the nail.

• Skin problems including itchy rashes, dry/cracked skin, or signs of infection.

Fertility Considerations

ERDAFITINIB may impact fertility in females who can become pregnant. Discuss any concerns with your healthcare provider.

Erdafitinib pi

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