Ledifos-Generic-Harvoni View larger

Ledifos (Sofosbuvir 400mg/Ledipasvir 90mg)

New product

$229.00

$229.00 per 28 Tablets

Indications & Dosage

Ledifos, also known as Hepcinat-LP, Myhep lvir” is a fixed-dose combination of Sofosbuvir and Ledipasvir indicated for the treatment of chronic hepatitis C virus (HCV). HARVONI combines Sofosbuvir 400mg and Ledipasvir90mg. Its Cure rates is 94% to 99% for hepatitis C. 

Ledifos is a generic prescription medicine from Hetero, which is one of the biggest pharmaceutical company in India.

Ledifos Dosage:

For the treatment of chronic hepatitis C infection.
For the treatment of chronic hepatitis C virus (HCV) genotype 1 infection.
Oral dosage
Treatment-naive Adults without cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks; however, an 8-week treatment duration can be considered for those patients with a baseline hepatitis C virus RNA less than 6 million international units/mL. Recommendation includes patients coinfected with HIV.

Treatment-naive Adults with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV.

Treatment-experienced Adults without cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV.

Treatment-experienced Adults with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 24 weeks. Alternatively, treatment duration may be reduced to 12 weeks if ledipasvir; sofosbuvir is administered in combination with ribavirin. Ribavirin must be administered with food in 2 divided doses, and the dose is based on weight as follows: less than 75 kg give 500 mg PO twice daily; 75 kg or more give 600 mg PO twice daily. Recommendation includes patients coinfected with HIV.

Treatment-naive and experienced Adults with decompensated (Child-Pugh B or C) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with ribavirin (600 mg PO once daily) for 12 weeks. Ribavirin must be administered with food, and if tolerated, the dose may be increased as follows: if less than 75 kg give 500 mg PO twice daily; if 75 kg or more give 600 mg PO twice daily. Consider decreasing ribavirin dose for abnormal hemoglobin. Recommendation includes patients coinfected with HIV. For patients unable to take ribavirin, guidelines recommend 1 tablet PO once daily for 24 weeks.

Treatment-naive and experienced Adults who have undergone liver transplantation and are without cirrhosis or have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with ribavirin for 12 weeks. Ribavirin must be administered with food in 2 divided doses, and the dose is based on weight as follows: less than 75 kg give 500 mg PO twice daily; 75 kg or more give 600 mg PO twice daily. Recommendation includes patients coinfected with HIV.

Treatment-naive and experienced Adults who have undergone liver transplantation and have decompensated (Child-Pugh B or C) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with low initial dose of ribavirin for 12 weeks as the preferred regimen. Increase ribavirin dose as tolerated.

Treatment-naive Children and Adolescents 12 to 17 years without cirrhosis or with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-experienced Children and Adolescents 12 to 17 years without cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-experienced Children and Adolescents 12 to 17 years with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 24 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-naive Children younger than 12 years weighing at least 35 kg without cirrhosis or with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-experienced Children younger than 12 years weighing at least 35 kg without cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-experienced Children younger than 12 years weighing at least 35 kg with compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 24 weeks. Recommendation includes patients coinfected with HIV. 

For the treatment of chronic hepatitis C virus (HCV) genotypes 5 or 6 infection.
Oral dosage
Treatment-naive and experienced Adults without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV.

Treatment-naive and experienced Adults with decompensated (Child-Pugh B or C) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with low initial dose of ribavirin for 12 weeks as a preferred regimen. Increase ribavirin dose as tolerated. For patients unable to take ribavirin, guidelines recommend 1 tablet PO once daily for 24 weeks.

Treatment-naive and experienced Adults who have undergone liver transplantation and are without cirrhosis or have compensated (Child-Pugh A) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with weight-based ribavirin for 12 weeks as a preferred regimen.

Treatment-naive and experienced Adults who have undergone liver transplantation and have decompensated (Child-Pugh B or C) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with low initial dose of ribavirin for 12 weeks as the preferred regimen. Increase ribavirin dose as tolerated.

Treatment-naive and experienced Children and Adolescents 12 to 17 years without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-naive and experienced Children younger than 12 years weighing at least 35 kg without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

For the treatment of chronic hepatitis C virus (HCV) genotype 4 infection.
Oral dosage
Treatment-naive and experienced Adults without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV.

Treatment-naive and experienced Adults with decompensated (Child-Pugh B or C) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with low initial dose of ribavirin for 12 weeks as a preferred regimen. Increase ribavirin dose as tolerated. For patients unable to take ribavirin, guidelines recommend 1 tablet PO once daily for 24 weeks.

Treatment-naive and experienced Adults who have undergone liver transplantation and are without cirrhosis or have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with ribavirin for 12 weeks. Ribavirin must be administered with food in 2 divided doses, and the dose is based on weight as follows: less than 75 kg give 500 mg PO twice daily; 75 kg or more give 600 mg PO twice daily. Recommendation includes patients coinfected with HIV.

Treatment-naive and experienced Adults who have undergone liver transplantation and have decompensated (Child-Pugh B or C) cirrhosis†

Guidelines recommend 1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with low initial dose of ribavirin for 12 weeks as the preferred regimen. Increase ribavirin dose as tolerated.

Treatment-naive and experienced Children and Adolescents 12 to 17 years without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Treatment-naive and experienced Children younger than 12 years weighing at least 35 kg without cirrhosis or who have compensated (Child-Pugh A) cirrhosis

1 tablet (90 mg ledipasvir; 400 mg sofosbuvir) PO once daily with or without food. The recommended duration of treatment is 12 weeks. Recommendation includes patients coinfected with HIV. 

Ledifos Side Effects:

Hepatitis B virus reactivation: Before starting treatment with Ledifos, your healthcare provider will do blood tests to check for hepatitis B virus infection. If you have ever had hepatitis B virus infection, the hepatitis B virus could become active again during or after treatment of hepatitis C virus with Ledifos. Hepatitis B virus becoming active again (called reactivation) may cause serious liver problems including liver failure and death. Your healthcare provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop taking 

Ledifos  PI

For more Prescribing information，please ask for “FDA Prescribing Information” from our customer supporter.

Additional Info

Package Quantity28
WarningsDon't take the drug without consulting a qualified doctor or physician.
Suggested useFollow the doctor's advice
Delivery & Returns7-14 Days

Reviews

Grade 
2019-02-27 21:50:43
Thanks

Hi Mr. Singh. Today, I got my 3 bottles of Ledifos (Harvoni). At first, I was skeptical to buy from you in India online, but I decided to trust you. I got the medicine so quick that I was surprised. I started my 12 week treatment today. I am so happy with your service and prompt replies, help and support. I owe you my health and for that, God bless you. Please, keep selling these medicines here in the USA are so expensive and not affordable for so many sick people. I would like you to please, publish this review so more people can trust you and buy with confidence. I found you on googling for India pharmaphy and you were there first and responded quickly to my order. Thank you so much for all the good you are doing to America. God bless you,

    Grade 
    2018-01-09 21:55:46
    thank you Bonhoa Pharmacy

    I would do it over again I choose 9 pm to take mine, I was told I had hep c 2017 at 61 yrs old ...it scared me to death now I say thank you after 8 weeks of treatment from Bonhoa Pharmacy and white blood cells great I'm healed and virus gone I give a big thank to the maker of this medicine and I never had a side effect, taking it at night. I feel great now and free of that hep c. Also Thank Mr.D.Singh and your colleagues's care. Hope more and more patients know your online pharmacy.

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