SoviHep (Sofosbuvir 400mg)

Sovihep (Sofosbuvir 400mg)’is a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor indicated for Hepatitis C medicine from Zydus, which is one of the biggest pharmaceutical company in India.

Sovihep（Sovaldi), is a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor indicated for the treatment of:

Adult patients with genotype 1, 2, 3 or 4 chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis as a component of a combination antiviral treatment regimen.

Pediatric patients 12 years of age and older or weighing at least 35 kg with genotype 2 or 3 chronic HCV infection without cirrhosis or with compensated cirrhosis in combination with ribavirin.

Sofosbuvir 400mg DOSAGE  

Testing Prior to the Initiation of Therapy: Test all patients for HBV infection by measuring HBsAg and anti-HBc

Recommended adult and pediatric dosage: One 400mg tablet taken once daily with or without food. 

HCV/HIV-1 coinfection:For adult and pediatric patients with HCV/HIV-1 coinfection, follow the dosage recommendations in the tables below, respectively

For more dosage, please check the FDA PI.

Sofosbuvir 400mg side effects:

Slow heart rate (bradycardia)

Sofosbuvir 400mg  treatment may result in slowing of the heart rate along with other symptoms when taken with amiodarone (Cordarone, Nexterone, Pacerone), a medicine used to treat certain heart problems. In some cases bradycardia has led to death or the need for a heart pacemaker when amiodarone is taken with Sofosbuvir 400mg. Get medical help right away if you take amiodarone with Sofosbuvir 400mg  and get any of the following symptoms:

fainting or near-fainting dizziness or lightheadedness

not feeling well • weakness • extreme tiredness • shortness of breath

• chest pain • confusion • memory problems

The most common side effects of Sofosbuvir 400mg when used in combination with ribavirin include: • tiredness • headache

The most common side effects of Sofosbuvir 400mg when used in combination with peginterferon alfa and ribavirin include:

• tiredness • nausea • low red blood cell count • headache • difficulty sleeping

Sofosbuvir 400mg PI

For more Prescribing information，please ask for “FDA Prescribing Information” from our customer supporter.