Geftinat (Gefitinib) 250mg

Geftinat (Gefitinib) 250mg is a tyrosine kinase inhibitor indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test.

Geftinat is a generic a tyrosine kinase inhibitor from Natco, which is one of the biggest listed pharmaceutical company in India.

Limitation of Use: Safety and efficacy of Gefitinib have not been established in patients whose tumors have EGFR mutations other than exon 19 deletions or exon 21 (L858R) substitution mutations. 

Gefitinib DOSAGE

Recommended dose is 250 mg orally, once daily with or without food

Geftinat Price & Cost

Generic Gefitinib 250mg (Geftinat)'s price is only 5% of brand one.

Gefitinib 250mg Side effect:

Gefitinib 250mg may cause serious side effects, including:

 lung or breathing problems. 

Gefitinib may cause inflammation of the lung that may lead to death. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening lung problems, or any combination of the following symptoms: trouble breathing or shortness of breath, cough, or fever.

 Iiver problems.

Gefitinib may cause inflammation of the liver that may lead to death. Tell your healthcare provider right away if you have any symptoms of a liver problem which may include:

o yellowing of your skin or the white part of your eyes (jaundice)

o dark or brown (tea colored) urine

o light-colored bowel movements (stools)

o decreased appetite o pain on the right side of your stomach (abdomen) Your healthcare provider will do blood tests to check your liver function during your treatment with Gefitinib.

 a tear in the wall of your stomach or intestines (perforation). Get emergency medical help right away if you have severe stomach (abdomen) pain.

 diarrhea. Diarrhea is common with Gefitinib and can sometimes be severe. Tell your healthcare provider right away if you have severe diarrhea or diarrhea that will not go away.

 eye problems. Tell your healthcare provider if you get watery eyes, sensitivity to light, blurred vision, eye pain, eye redness, or vision changes.

 skin reactions. Skin redness, rash, itching, and acne are common with Gefitinib. This may occur on any part of your body. Get medical help right away if you develop severe skin reactions such as peeling or blistering of your skin. Gefitinib may cause fertility problems in females. Talk to your healthcare provider if you plan to become pregnant. 

New Package:

From September, 2018 Natco started to use the new package for Geftinat( Gefitinib) 250mg.